ARPA-H ADVOCATE Program

The Advanced Research Projects Agency for Health (ARPA-H) Agentic AI-Enabled Cardiovascular Care Transformation (ADVOCATE) program will enable the development of an Agentic system that delivers autonomous and semi-autonomous clinical care directly to patients with cardiovascular disease (CVD).

ADVOCATE seeks leaders in the tech sector, academia, non-profit organizations, and small businesses to overcome the technical, regulatory, and market barriers holding back innovation in clinical agentic AI. The program has three technical areas: development of a patient-facing clinical AI agent, a supervisory agent that ensures clinical AI agents’ consistent safety and effectiveness, and a scalable plan for integration into clinical workflows in healthcare organizations.

As a part of this opportunity, one of the technical areas (TA3) ARPA-H is focused on is integrating the deployment of an AI in a  healthcare organization; specifically, ARPA-H is focused on health care systems that can supply high-quality longitudinal data that can be used to fine-tune AI agents.  A seemingly good fit for VA.

ARPA-H invites interested parties to review the solicitation, which is posted and maintained on SAM.gov. The solicitation outlines the opportunity and its requirements, key dates and deadlines, submission documents and templates, evaluation criteria for submissions, and information on how to apply.

Key Details:

• Solution Summaries Due: Feb 27th, 2026.

  A summary is required to submit a full proposal.

• Full Proposal Due: April 1, 2026.

Ready to apply? To submit a Solution Summary, sign-in to the ARPA-H Solutions Portal. 

More info: https://arpa-h.gov/explore-funding/programs/advocate