S1802: Prostate Cancer Therapy Outcomes
This phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants with prostate cancer that has spread to other places in the body. Addition of prostate removal surgery or radiation therapy to standard systemic therapy for prostate cancer may lower the chance of the cancer growing or spreading.
M22-128: EPICORE DLBCL-4
This study is evaluating a combination of epcoritamab and lenalidomide for older adults with relapsed or refractory diffuse large B-cell lymphoma (DLBCL), aiming to improve treatment outcomes and response rates.
FORTE
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps (FORTE) is a colorectal cancer prevention study looking to answer the question: when should patients who had 1-2 small benign polyps (adenomatous polyps/adenomas) removed during colonoscopy have repeat surveillance colonoscopy?
IRAKLIA
The purpose of the study is to compare the subcutaneous (SC) injection using an investigational wearable injector device to intravenous (IV) infusion of isatuximab in combination with pomalidomide and dexamethasone for patients with relapsed/refractory multiple myeloma (RRMM).
S1918: New Approaches for Lymphoma in Older Adults with Aggressive Variants
This phase II/III trial compares the side effects and activity of oral azacitidine in combination with the standard drug therapy (reduced dose rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone [R-miniCHOP]) versus R-miniCHOP alone in treating patients 75 years or older with newly diagnosed diffuse large B cell lymphoma.
REFLECTION: Early Cancer Detection
The Reflection study is enrolling Veterans who have opted to be screened with Galleri, a multi-cancer early detection blood test which can detect the presence of 50+ cancers at time of blood draw.